AHN Quality & Safety Virtual Grand Rounds with Oren Guttman, MD, MBA

Oren Guttman, MD, MBA serves as System Vice President for Patient Safety at Jefferson Health, a 33‑hospital, $14.5B integrated health system serving Pennsylvania and Southern New Jersey, with more than 65,000 employees, including 12,800 nurses, 7,800 physicians, and 9,400 learners. He maintains an active clinical and academic role as Professor of Anesthesiology and Peri‑operative Medicine at Sidney Kimmel Medical College.

Dr. Guttman’s career is dedicated to advancing patient safety at enterprise scale. He is a nationally and internationally recognized physician‑executive, author, and thought leader in the practical translation of resiliency engineering, applied human factors, and modern safety science into healthcare operations. He is the principal architect of Jefferson Health’s Safety Management System—an enterprise framework integrating resiliency engineering, clinically informed human factors, and contemporary safety science into day‑to‑day clinical operations. This work received international recognition with the 2021 ECRI Safety Excellence Award and serves as a foundational platform for the Institute for Healthcare Improvement’s careOS operating system redesign initiative.

His work advancing a new paradigm for patient safety has been featured in NEJM Catalyst (December 2025) and widely covered by The Wall Street Journal, Becker’s Hospital Review, and Healthcare Tech Outlook. During the COVID‑19 pandemic, his focus on anticipatory risk management and prevention of harm—particularly through resiliency‑engineered approaches to reducing healthcare‑associated infections such as CLABSIs—contributed to Jefferson Health being named to HIMSS’ Davies Award case studies (2022) and receiving the HAP Safety Excellence Award (2023).

Dr. Guttman is a member of the Anesthesia Patient Safety Foundation (APSF) and serves as an advisor and consultant on the application of safety science and human factors in healthcare for organizations including the American Hospital Association, Institute for Healthcare Improvement, ECRI, Agency for Healthcare Research and Quality, CMS, and others.

Outside of his professional work, Dr. Guttman is an avid reader with interests spanning ancient Judeo‑Christian literature (in Aramaic), neuroscience, tort law, and behavioral economics. He enjoys attending professional sporting events with his children, barbequing, and blending his own coffee. He speaks four languages fluently and is actively learning a fifth.