At the completion of this activity, the participant will be able to:
1.   Explain current guideline recommendations for the use of tenecteplase in acute ischemic stroke
2.  Describe the pharmacokinetic and pharmacodynamics differences between alteplase and tenecteplase
3.  Review comparative primary literature  of  tenecteplase versus alteplase for acute ischemic stroke
4.  Discuss the impact of implementing tenecteplase for acute ischemic stroke at other institutions