At the completion of this activity, the participant will be able to:

1. Define the term “prolonged-infusion beta-lactams” and how they are different from traditional infusions of beta-lactams
2. Describe the pharmacokinetic basis for use of prolonged-infusion beta-lactams over traditional intermittent beta-lactams
3. Summarize consensus recommendations on the use of prolonged infusion beta-lactams
4. Describe literature supporting the use of prolonged-infusion beta-lactams over traditional infusions in critically ill patients