At the completion of this activity, the participant will be able to:
1. Describe the pharmacologic and pharmacokinetic characteristics of methadone relevant to opioid use disorder treatment and clinical practice.
2. Discuss emerging evidence regarding methadone treatment in the fentanyl era, including accelerated induction protocols, evolving therapeutic dose targets, and recent literature evaluating higher-dose methadone strategies.
3. Apply evidence-based approaches to methadone dose verification, management of missed doses, and coordination of care involving opioid treatment programs.
4. Evaluate clinical scenarios involving opioid treatment program regulations, take-home methadone flexibilities, and use of the federal 72-hour rule to support continuity of care